Studies on Eco-friendly Solid Acid Catalysts for the Synthesis of 4-Chloro, 4’-Hydroxy Benzophenone by Friedel-Crafts Acylation Reaction.
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چکیده
منابع مشابه
Biocatalytic Friedel–Crafts Acylation and Fries Reaction
The Friedel-Crafts acylation is commonly used for the synthesis of aryl ketones, and a biocatalytic version, which may benefit from the chemo- and regioselectivity of enzymes, has not yet been introduced. Described here is a bacterial acyltransferase which can catalyze Friedel-Crafts C-acylation of phenolic substrates in buffer without the need of CoA-activated reagents. Conversions reach up to...
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The Friedel–Crafts acylation of 2-methoxynaphthalene was carried out in the liquid-phase batch conditions using Hmordenite, H-beta and H-Y zeolite as catalysts. All the catalysts showed 35–40% conversion in the temperature range of 100–150◦C. 1-Acyl-2-methoxynaphthalene was formed as the primary product. When acetyl chloride was used as the acylating agent, a higher yield of 6-acyl-2-methoxynap...
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A new, facile, cost effective, and eco-friendly protocol is reported for the synthesis of 2,3-dihydroquinazoline-4-(1H)-ones exploring tannic acid as a novel, inexpensive, andbiodegradable catalyst. A variety of dihydroquinazolins were prepared from aromatic aldehydesand anthranilamide using catalytic amount of tannic acid under solvent free conditions.Operational simplicity, high yield, and hi...
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The synthesis of the title compound is described. This compound was found to be active (3c) against a number of pathogenic microorganisms in vitro. It is a non-absorbable antibacterial topically and its pharmacologic studies revealed that it is a non-toxic agent with a wide range of safety. It proved to be effective in the prevention and treatment of pseudomonaswound infections in voluntee...
متن کاملNovel synthesis of optically active bishomotyrosine derivatives using the Friedel-Crafts reaction in triflic acid.
We report here a novel synthesis of optically active bishomotyrosine. The bishomotyrosine skeleton was constructed by using a Friedel-Crafts reaction between phenol and optically active N-Tfa-Glu(Cl)-OMe in triflic acid under the mild condition. Reduction and subsequent deprotection then afforded bishomotyrosine derivatives without any loss of optical purity.
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ژورنال
عنوان ژورنال: International Journal for Research in Applied Science and Engineering Technology
سال: 2020
ISSN: 2321-9653
DOI: 10.22214/ijraset.2020.4036